In a world where science and adventure intertwine, a group of young scientists embarks on a mission that will change their lives forever. Reed Richards, a brilliant but socially awkward physics student, convinces his best friend, Johnny Storm, a daring pilot, and his older sister, engineer Sue Storm, to join him in an ambitious experiment at a particle accelerator. As the mission unfolds, a series of catastrophic failures leads to exposure to unknown radiation, transforming each of them in unexpected ways.