In a luxurious Manhattan home, Meg and her daughter Sarah are ready to start a new life, leaving behind a complicated past. Everything seems to be going smoothly until a group of armed intruders bursts into their home. What was supposed to be a refuge becomes a deadly trap. To save themselves, mother and daughter are forced to take shelter in a panic room, a small fortified room designed to protect its occupants from all types of threats.
While the thieves, who have a particular interest in the house's safe, search tirelessly throughout the place, Meg and Sarah must navigate a series of critical decisions. As the tension rises, the mother will fight not only for her survival but also to save her daughter from an uncertain fate. Inside this improvised stronghold, time is working against them and their wits are put to the test as they try to communicate with the outside world and attract the attention of the authorities.
As the story unfolds, we discover that each member of the intruder group has their own secrets and motivations, complicating the situation. The intense struggle for survival turns into a cat-and-mouse game, where emotions and family ties become entangled in the chaos. This adrenaline-fueled movie, filled with surprising twists, redefines the battle between good and evil in a claustrophobic setting.