In a distant future, Earth has been destroyed by a powerful alien race known as the Drej, who seek to eliminate humanity. As human civilization crumbles, a young man named Cale Tissot, son of a brilliant scientist, becomes the key to the survival of the human race. Cale holds in his memory the blueprint for a project called Titan, a spacecraft designed to find a new home for humanity.
With Earth as a distant memory, Cale embarks on an exciting intergalactic adventure alongside a group of peculiar allies. Among them are a cynical ship captain, a young warrior with exceptional skills, and a strange yet endearing alien with a sparkling personality. Together, they must face not only the fearsome Drej, who continue to seek the annihilation of the last remnants of humanity, but also their own fears and doubts as they attempt to uncover the whereabouts of the legendary Titan.
As the plot unfolds, Cale realizes that his destiny is irrevocably tied to the future of all humankind. The film combines spectacular action sequences with moments of comedy and emotional drama, all wrapped in a stunning animation style that makes it stand out. Through his odyssey, Cale will learn about hope, redemption, and the importance of finding a place to call home in the vast and dangerous universe.