Two years after the terrifying events in Woodsboro, life seems to have returned to normal for Sidney Prescott. Now a film student at the University of Windsor, she is trying to leave the trauma of the past behind. But horror comes chasing her again when a new killer, inspired by the infamous "Stab" movies, begins to hunt down students on campus.
Sidney, along with her friend Randy, who is still obsessed with the rules of horror movies, and her new boyfriend Derek, find themselves caught in a deadly game that feels all too familiar. As bodies begin to pile up, panic spreads across the university, and paranoia becomes a way of life. Everyone becomes a suspect, and trust and loyalty are put to the test in a world full of intrigue.
Additionally, the arrival of Gale Weathers, the reporter who covered the Woodsboro murders, adds a new layer of tension. Secrets from the past resurface, and Sidney faces the difficult reality that the killer may be closer than she imagines. As they unravel the truth, surprises and unexpected twists lead the trio to question their own lives and the fragility of security. In this sequel, the story of the killer becomes more complex and dangerous, challenging the notion that evil can be eradicated. Who will be the next to fall?