In a transatlantic commercial flight, the journey begins routinely, but things take an unexpected turn when a group of deadly snakes is unleashed in the cabin. Chaos ensues when FBI agent Neville Flynn boards the plane with the mission of escorting a key witness for a crucial trial against a feared crime boss. However, in an attempt to sabotage the operation, the criminal has planned a chilling revenge: to release a variety of venomous snakes during the flight.
As the snakes begin to attack unsuspecting passengers, the tension escalates and panic takes over the cabin. The passengers, a diverse group ranging from a daring young man to a dysfunctional family and a condescending flight attendant, must band together to survive as they confront their greatest fear. Flynn must act quickly, coordinating efforts with the crew and using his experience to contain the situation before widespread panic leads to disaster.
In a mix of relentless action, unexpected laughter, and moments of sheer horror, the flight turns into a fight for survival. Will the passengers find a way to overcome this deadly situation before the plane lands? The adrenaline is at its peak in this race against time and reptiles.