In a world where humans have discovered the existence of vampires and liches, the warriors of the night are forced to come out of the shadows. The story follows Selene, a powerful vampire, who awakens after a long period of cryogenization. Upon opening her eyes, she realizes that everything has changed: humanity has taken drastic measures to eradicate the creatures of the night, and werewolves have evolved even further, inciting fear about their existence.
Disoriented and alone, Selene embarks on a mission to uncover what has happened while she was in hibernation. Soon, she realizes that not only is her species in danger, but also her own daughter, a hybrid creature who might be the key to the survival of vampires and liches. With a group of unexpected allies by her side, Selene faces hunters and a new breed of predators seeking to exterminate everything that moves.
As the plot unfolds, the struggle intensifies, and Selene must navigate through betrayals, old enemies, and new alliances. With her life and her daughter's at stake, she is forced to confront what she has always hidden: her humanity. The film combines thrilling action and shocking revelations in an epic conflict between the forces seeking dominance and those fighting to survive in a world that no longer belongs to them.