In an explosive mix of comedy and action, we follow Dale Denton, a pizza delivery guy who is also a hardcore stoner. His life takes an unexpected turn when he witnesses a murder while visiting his quirky marijuana supplier, Saul Silver. Realizing that the killer is a corrupt cop and his life is in danger, Dale decides to flee with Saul. The pair, who couldn't be more different, attempts to navigate a chaos of outrageous situations while trying to escape their pursuers.
As the plot unfolds, the duo encounters a series of eccentric characters and absurd situations, from a group of mobsters to a chalet filled with weapons. Laughter intertwines with adrenaline, as Dale and Saul, completely out of their depth and lacking experience in these kinds of confrontations, must use their wits (and their stash) to survive. What begins as a simple odyssey to escape from criminals turns into a wild adventure that tests their friendship and their ability to handle extreme situations.
With hilarious dialogues and unexpected moments, this comedy becomes a journey where humor and action intertwine, as our protagonists try to get out of a mess they couldn't have imagined even in their worst nightmares. All of this, due to a simple miscalculation and a "Pineapple Express."