In the bustling city of New York, a young man named Peter Parker, a nerd struggling to fit in at school, becomes the target of bullying. Everything changes when he is bitten by a radioactive spider during a scientific field trip, granting him amazing powers, such as the ability to climb walls, superhuman strength, and a spider-sense that warns him of imminent danger. With these new abilities, Peter finds himself at a crossroads: to use his powers for good or to take advantage of them for personal gain.
After the heartbreaking death of his beloved Uncle Ben, which occurs just after Peter decides not to act when he had the chance to stop a thief, the young man vows that he will never again stand idly by. Bearing the weight of his responsibility, he becomes the hero that New York needs in its fight against crime. Meanwhile, he faces personal challenges, such as his unrequited love for Mary Jane Watson, the girl of his dreams, and his complicated relationship with his best friend, Harry Osborn, whose father, Norman, harbors a dark secret.
When Norman becomes the lethal Green Goblin, their paths collide in an epic battle that will not only test Peter’s skills as Spider-Man but also his values and his ability to cope with guilt and loss. As he struggles to balance his personal life and his life as a hero, Peter learns that with great power comes great responsibility.