In this hilarious sequel, the first family of comedy is back and ready to wreak havoc. Greg Focker, the nice guy who has been through a thousand embarrassing situations, is preparing to introduce his parents to his father-in-law, Jack Byrnes, a former CIA agent who hasn't stopped being a bit paranoid. The meeting is highly anticipated, as Greg's family is the complete opposite of Jack's rigorous and controlling family.
Greg's parents, the superficial and carefree Bernie and Roz, arrive with their unique eccentricities and a hippie worldview that promises to clash completely with the Byrnes' strict lifestyle. Meanwhile, Jack goes into detective mode to figure out if his grandson's future grandparents can be trusted. Amid misunderstandings, awkward situations, and a series of hilarious misadventures, the two clans confront their differences, from parenting styles to family traditions.
Greg's attempts to impress his future in-laws become even more complicated when family secrets and rivalries come to light. What should be a big family gathering turns out to be a real circus full of explosive interactions. In the end, love and family acceptance are put to the test in the funniest way possible, reminding us that, despite our differences, we are all part of the same family craziness.