Alice Howland is a brilliant linguistics professor at Columbia University who, at the age of 50, leads a fulfilling life with a successful career and a loving family composed of her husband John and their three children, who seem to be on the path to a promising future. But everything changes when she begins to experience episodes of forgetfulness and confusion, prompting her to seek medical help. After a series of tests, she receives the devastating diagnosis of early-onset Alzheimer's, a type of dementia that affects much younger individuals.
As the disease progresses, Alice struggles to maintain her identity and independence, facing an uncertain future. The film portrays her effort to hold onto her memories and professional life, while her family, especially her husband and children, navigate the painful process of watching their wife and mother change in an irreversible manner. The impact of the diagnosis creates tensions and difficult decisions, leading each family member to reevaluate their relationship with Alice and with one another.
In this emotional journey, the story addresses universal themes such as loss, love, and resilience, all seen through the eyes of a woman who, despite adversity, seeks to persevere and enjoy every moment, even as the future she once viewed as clear becomes blurred.