In a world where science and love collide in unexpected ways, a shy and clumsy chemistry professor, Sherman Klump, feels trapped in his life. With a heart of gold and an overweight frame that makes him the target of ridicule, Sherman yearns to leave his mark on the world, especially in the realm of romance. However, his life takes a radical turn when he discovers a magic formula that allows him to transform into a thin, charismatic version of himself: Buddy Love.
At first, the transformation seems to be the key to everything he desires. Buddy is funny, self-assured, and, above all, irresistible to women. Sherman quickly falls in love with his coworker, the lovely Carla, who is captivated by Buddy's daring personality. But as Buddy's adventures intensify, Sherman realizes that taking on this new identity comes at a cost.
Problems arise when the duality of his existence begins to overflow, and the line between Sherman and Buddy becomes increasingly blurred. In a series of comedic and heartfelt situations, Sherman embarks on a journey of self-discovery that will teach him about true confidence, personal acceptance, and self-love. Amid laughter and touching moments, this story of transformation will challenge his ideas about beauty and what it truly means to be oneself.