The story picks up right where the previous installment left off, with Detective Eric Matthews facing the devastating consequences of his encounter with Jigsaw. As chaos ensues following Matthews's death, the macabre game continues with a new group of victims. The new protagonist is a forensic expert, Dr. Lynn Denlon, who finds herself trapped in Jigsaw's twisted web of manipulations. What begins as a simple assessment of a crime scene turns into a desperate fight for survival.
Lynn is forced to operate on Jigsaw mid-action, adding a layer of tension to the plot. Jigsaw's master plan is not just a game of life and death; it is a reflection of his own views on the value of life and sacrifice. Furthermore, the film poses the question of how far one would go for those they love.
Meanwhile, another group of characters grapples with carrying out the cruel and unusual exercises Jigsaw has set up, challenging not only their physical endurance but also their morality. With unexpected twists and shocking revelations, the viewer finds themselves caught in a labyrinth of intrigue and horror, where the only certainty is that no one is safe. As the pieces of the puzzle come together, Jigsaw's legacy is revealed in all its dark complexity, leading everyone to question their own limits.